EssilorLuxottica is proud to announce significant six-month interim results from an ongoing randomized, double-masked clinical trial in China evaluating Essilor Stellest 2.0 lenses in myopic children. At six months, Essilor Stellest 2.0 lenses achieved treatment effects, compared to single vision lenses, of 0.51 D for myopia progression and 0.21 mm for axial elongation on average. These effects were comparable to those previously reported after 12 months with first-generation Essilor Stellest lenses, indicating a potential accelerated treatment response.†1,2
“We are excited by these six-month interim findings for Essilor Stellest 2.0 lenses, which represent an important milestone in our long-term commitment to advancing myopia management through continuous innovation and clinical research,” commented Davide Schinetti, Chief Operating and R&D Officer at EssilorLuxottica. “The magnitude and speed of the treatment response observed at six months are very encouraging and have not been previously observed across our Stellest clinical research ever.”
“I’m greatly encouraged by the six-month interim results. Notably, with myopia progression remaining close to 0 D on average after six months, spectacle lenses with H.A.L.T.* MAX technology achieved in just half a year the same level of myopia control – on both refraction and axial length – that was previously reported with H.A.L.T.* technology at one year. That means the treatment response appears to be effectively twice as fast. High wearing compliance, rapid adaptation, and consistent efficacy across younger and older children reinforce the practical value of this innovation in myopia control. These findings add important clinical evidence from China to the global body of research on H.A.L.T.* MAX technology,” said Prof. Yang Xiao, Principal Investigator, Zhongshan Ophthalmic Center, Sun Yat-sen University, China.
The six-month interim results were first presented during an EssilorLuxottica satellite symposium at the World Society of Paediatric Ophthalmology and Strabismus (WSPOS) Subspecialty Day, held during the European Society of Cataract and Refractive Surgeons (ESCRS) Congress in London.
Key interim findings included:
- Significant slowing of myopia progression and axial elongation on average, compared with single-vision spectacle lenses, with treatment effects of 0.51 D and 0.21 mm respectively.‡1
- High wearing compliance, with more than 90% of children in both groups wearing their spectacles for more than 12 hours per day, seven days per week.§
- Adaptation and wearer comfort were as good as with single-vision lenses, with 98% of children fully adapting within one week.¶1
The study remains ongoing, with participants continuing to be followed to evaluate longer-term efficacy and safety. The prespecified one-year analysis will serve as the primary efficacy endpoint.‡1
The findings provide the first randomized, double-masked clinical evidence for Essilor Stellest 2.0 lenses from China and are consistent with the clinical performance previously observed in the randomized contralateral crossover clinical trial in Singapore, whose findings were published in Translational Vision Science & Technology in 2025.3 Together, the Singapore and China studies demonstrate consistent clinical performance across study designs, further strengthening the global clinical evidence for Essilor Stellest 2.0 lenses and reinforcing EssilorLuxottica’s long-standing commitment to advancing one of the most comprehensive clinical research programs in spectacle lens-based myopia management.
Notes:
This communication is intended for scientific exchange only and does not constitute medical or treatment recommendations.
Essilor Stellest lens regulatory status and product availability may vary by country. U.S. FDA authorization and indications for use are based solely on clinical trial data from the U.S.
Essilor® Stellest® 2.0 lenses are currently not available in all countries, including the United States, and have not been cleared by the FDA in the U.S.
*H.A.L.T. is an acronym for Highly Aspherical Lenslet Target and does not imply a “halt” or “stop” of myopia progression.
† Based on interim results from an ongoing two-year, randomized, double-masked clinical trial in China (n=62 Essilor® Stellest ® 2.0; n=58 single vision). Indirect comparison across separate randomized clinical studies. Treatment effects versus single vision lenses were SER: 0.51 D and AL: 0.21 mm on average at six months in the ongoing Essilor® Stellest® 2.0 lens two-year, randomized, double-masked, two-arm clinical trial conducted in Guangzhou, China, compared with SER: 0.53 D and AL: 0.23 mm on average at 12 months in the Essilor® Stellest® lens two-year prospective, controlled, randomized, double-masked clinical trial conducted in Wenzhou, China. The studies differed in population, participant age groups, location, design, and follow-up duration (6 vs 12 months), and no formal between-study statistical comparison was performed.
‡ Interim results from a two-year, randomized, double-masked clinical trial in China among 62 children wearing Essilor® Stellest® 2.0 lenses vs 58 wearing single-vision lenses.
§ In the clinical trial, over 90% of children wore their spectacles for more than 12 hours per day, 7 days per week.
¶ Interim results from a two-year, randomized, double-masked clinical trial in China among 63 children wearing Essilor® Stellest® 2.0 lenses vs 60 wearing single-vision lenses.
1 Essilor International. Data on File, 2026.
2 Bao J, Yang A, Huang Y, Li X, Pan Y, Ding C, et al. One-year myopia control efficacy of spectacle lenses with aspherical lenslets. Br J Ophthalmol. 2022 Aug;106(8):1171–6.
3 Raveendran RN, et al. Effect of increased power and asphericity of highly aspherical lenslets on myopia control efficacy: a contralateral crossover study. Transl Vis Sci Technol. 2025;14(11):9.
